Description

Ethyl-(2S,3S)-(p-Nitrophenyl)-Oxirane-2,3-Dicarboxylate is a high-purity chiral epoxide derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its defined stereochemistry and reactive oxirane ring make it a valuable building block for constructing complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, including protease inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is crucial for activity.
• Asymmetric Synthesis: Employed as a starting material or reagent in stereoselective reactions to introduce the (2S,3S) configuration into target compounds.
• Chemical Biology Probes: Useful for creating labeled or modified compounds to study biological pathways and enzyme mechanisms.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialized polymers with unique optical or mechanical properties.
• Academic & R&D: Serves as a reference standard and reagent in university and corporate research laboratories for methodological development.

Basic Information

Item	Details
Product Name	Ethyl-(2S,3S)-(p-Nitrophenyl)-Oxirane-2,3-Dicarboxylate
CAS No.	100464-19-5
Molecular Formula	C₁₃H₁₃NO₇
Molecular Weight	295.25 g/mol
Synonyms	Diethyl (2S,3S)-2,3-Epoxy-3-(4-nitrophenyl)succinate; (2S,3S)-Diethyl 2,3-Epoxy-3-(4-nitrophenyl)succinate; Ethyl (2S,3S)-3-(4-Nitrophenyl)oxirane-2,3-dicarboxylate; (2S,3S)-Diethyl 3-(4-nitrophenyl)oxirane-2,3-dicarboxylate; (2S,3S)-Epoxysuccinic Acid Diethyl Ester 4-Nitro Derivative; (2S,3S)-ONPS Diethyl Ester; trans-Diethyl 3-(4-Nitrophenyl)oxirane-2,3-dicarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl-(2S,3S)-(p-Nitrophenyl)-Oxirane-2,3-Dicarboxylate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.