Description

1H-Pyrrolizine-2-Carboxaldehyde, Hexahydro-5-Oxo-, cis- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in complex multi-step syntheses, particularly for constructing nitrogen-containing heterocyclic frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the creation of compound libraries for drug discovery.
• Asymmetric Synthesis: Utilized as a precursor or reagent in catalytic asymmetric reactions due to its defined cis-configuration.
• Fine Chemical Production: Serves as a specialty intermediate in the manufacture of high-value agrochemicals or performance chemicals.

Basic Information

Product Name	1H-Pyrrolizine-2-Carboxaldehyde, Hexahydro-5-Oxo-, cis- (9Ci)
CAS No.	100447-28-7
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	cis-Hexahydro-5-oxo-1H-pyrrolizine-2-carboxaldehyde; (3aS,7aR)-Hexahydro-5-oxo-1H-pyrrolizine-2-carbaldehyde; 2-Formylhexahydro-5-oxo-1H-pyrrolizine, cis-; 1H-Pyrrolizine-2-carboxaldehyde, hexahydro-5-oxo-, (3aS-cis)-; (3aS,7aR)-Octahydro-5-oxo-1H-pyrrolizine-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of our 1H-Pyrrolizine-2-Carboxaldehyde, Hexahydro-5-Oxo-, cis- (9Ci) is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our standard analytical suite includes identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of specific impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.