Description

5-(Chloromethyl)-3-(Trifluoromethyl)-1,2,4-Oxadiazole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a reactive chloromethyl group and a stable trifluoromethyl-substituted oxadiazole ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group can enhance biological activity and stability.
• Material Science Research: Serves as a precursor for functional polymers and advanced materials with specific electronic or surface properties.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Fluorine Chemistry: A valuable substrate for further fluorination reactions and the study of structure-activity relationships (SAR) in fluorine-containing compounds.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	5-(Chloromethyl)-3-(Trifluoromethyl)-1,2,4-Oxadiazole
CAS No.	100442-49-7
Molecular Formula	C4H2ClF3N2O
Molecular Weight	186.52 g/mol
Synonyms	3-(Trifluoromethyl)-5-(chloromethyl)-1,2,4-oxadiazole; 5-Chloromethyl-3-trifluoromethyl-1,2,4-oxadiazole; 1,2,4-Oxadiazole, 5-(chloromethyl)-3-(trifluoromethyl)-; CTFO; Oxadiazole chloromethyl trifluoromethyl derivative
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)-3-(Trifluoromethyl)-1,2,4-Oxadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.