Description

1-Benzyloxy-4-Chloro-2-Iodo-Benzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and a benzyloxy protecting group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated benzene core.
• Material Science Research: Serves as a specialized monomer or building block for creating advanced organic materials, such as liquid crystals or organic semiconductors.
• Chemical Biology & Proteomics: Employed as a derivatization agent or a tag in the development of molecular probes and biochemical tools.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways in contract research organizations (CROs).

Basic Information

Product Name	1-Benzyloxy-4-Chloro-2-Iodo-Benzene
CAS No.	100398-25-2
Molecular Formula	C13H10ClIO
Molecular Weight	344.57 g/mol
Synonyms	4-Chloro-2-iodo-1-(phenylmethoxy)benzene; 1-Chloro-4-(benzyloxy)-2-iodobenzene; Benzene, 1-(benzyloxy)-4-chloro-2-iodo-; 2-Iodo-4-chlorophenyl benzyl ether; 4-Chloro-2-iodophenyl benzyl ether; 1-Benzyloxy-4-chloro-2-iodobenzene; (4-Chloro-2-iodophenoxy)methyl]benzene
EINECS	Contact for details

Quality Control

Our 1-Benzyloxy-4-Chloro-2-Iodo-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.