Description

4-o-Acetyl-21-o-De(Aminocarbonyl)-27-Demethoxy-4-O,23,26-Tridemethyl-6-Deoxo-25-Deoxy-6-(2,3-Dimethoxy-1-Oxopropoxy)-27-Methyl-25-Oxokabiramide C is a structurally complex, semi-synthetic derivative of the kabiramide family of macrolide compounds. This molecule is of significant interest in advanced pharmaceutical research and development due to its potential as a key intermediate or a lead compound for novel therapeutic agents. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in oncology, antimicrobial, or other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel, potent macrolide-based drug candidates.
• Biochemical Research: Used as a reference standard or a probe in studies investigating actin-binding mechanisms, cytoskeleton dynamics, and cell motility.
• Anticancer Agent Development: Explored for its potential cytotoxic properties and structure-activity relationships (SAR) in oncology research.
• Antimicrobial Research: Investigated for activity against fungi, parasites, or drug-resistant bacterial strains, leveraging the core kabiramide scaffold.
• Chemical Biology Tool: Utilized to study specific biological pathways and protein interactions due to its targeted bioactivity.
• Process Chemistry & Scale-Up: Supplied to support route scouting, optimization, and pilot-scale production of advanced active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-o-Acetyl-21-o-De(Aminocarbonyl)-27-Demethoxy-4-O,23,26-Tridemethyl-6-Deoxo-25-Deoxy-6-(2,3-Dimethoxy-1-Oxopropoxy)-27-Methyl-25-Oxokabiramide C
CAS No.	100045-74-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Kabiramide C derivative; 27-Demethoxy-27-methyl-25-oxokabiramide C 4-acetate 6-(2,3-dimethoxy-1-oxopropoxy) derivative; 4-O-Acetyl-6-O-(2,3-dimethoxy-1-oxopropyl)kabiramide C derivative; 25-Oxo-27-methylkabiramide C modified derivative; Demethylated/Oxidized Kabiramide C analog
EINECS	Contact for details

Quality Control

Our 4-o-Acetyl-21-o-De(Aminocarbonyl)-27-Demethoxy-4-O,23,26-Tridemethyl-6-Deoxo-25-Deoxy-6-(2,3-Dimethoxy-1-Oxopropoxy)-27-Methyl-25-Oxokabiramide C is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure structural identity and high purity. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.