Description

(2R,3S)-1,2-Epoxy-3-Hydroxy-4-Pentene is a high-value chiral epoxide building block, essential for the stereoselective synthesis of complex organic molecules. Its defined stereochemistry and bifunctional nature make it a critical intermediate for creating pharmaceuticals and fine chemicals with high optical purity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of antiviral agents, enzyme inhibitors, and other bioactive molecules requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where the biological activity is stereospecific.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and catalysts used in enantioselective chemical transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that demand high enantiomeric purity.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis and stereochemistry studies.
• Polymer Modification: Can be used to introduce epoxy and hydroxyl functionalities into polymer chains for cross-linking or property enhancement.

Basic Information

Product Name	(2R,3S)-1,2-Epoxy-3-Hydroxy-4-Pentene
CAS No.	100017-22-9
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	(2R,3S)-3-Hydroxy-1,2-epoxy-4-pentene; (2R,3S)-3-Hydroxypent-4-en-1,2-epoxide; (2R,3S)-1,2-Epoxy-3-hydroxypent-4-ene; (2R,3S)-Glycidol derivative; (2R,3S)-Epoxy alcohol; 4-Penten-1,2-epoxy-3-ol, (2R,3S)-; Chiral glycidol; (2R,3S)-Pentenoxide alcohol
EINECS	Contact for details

Quality Control

Our (2R,3S)-1,2-Epoxy-3-Hydroxy-4-Pentene is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric excess. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC analysis, to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its epoxide functionality and light sensitivity, prolonged exposure to light or elevated temperatures should be avoided to maintain product stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.