Description

Phorbol 12,13,20-Triacetate, 4Beta is a highly specific and potent diterpene ester derivative of phorbol. This compound is a critical biochemical tool for the study of protein kinase C (PKC) signaling pathways and cellular responses. It is primarily utilized by researchers and developers in life sciences, pharmacology, and toxicology for its ability to act as a tumor promoter and modulate cellular processes. The product is supplied to meet the stringent requirements of advanced research and development applications.

Application

• Biochemical Research: As a potent activator of protein kinase C (PKC) isoforms for studying signal transduction, cell proliferation, and differentiation.
• Pharmacology & Toxicology: Used in mechanistic studies of tumor promotion, inflammation, and immune response modulation.
• Cell Biology: A key reagent for inducing specific cellular responses in vitro, including apoptosis studies and gene expression analysis.
• Drug Discovery: Serves as a reference standard and a tool compound for screening and validating potential PKC-targeted therapeutics.
• Academic Research: Fundamental research in molecular biology and cancer biology to elucidate complex biological pathways.

Basic Information

Product Name	Phorbol 12,13,20-Triacetate, 4Beta
CAS No.	19891-05-5
Molecular Formula	C28H36O9
Molecular Weight	516.58 g/mol
Synonyms	4β-Phorbol 12,13,20-Triacetate; Phorbol 12,13,20-Triacetate; 12-O-Tetradecanoylphorbol-13-acetate analog; TPA analog; 4β-Phorbol Triacetate; NSC 406042; PKC Activator (Phorbol Ester); 1,1a,1b,4,4a,7a,7b,8,9,9a-Decahydro-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one 12,13,20-triacetate
EINECS	Contact for details

Quality Control

Our Phorbol 12,13,20-Triacetate, 4Beta is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot undergoes comprehensive analytical testing, including identity confirmation and purity assessment by advanced chromatographic methods. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under inert atmosphere. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.