Description

1-(1,1-Dimethylethyl)-2-(1,1-Dimethyl-2-Phenylethyl)Diaziridin-3-One is a specialized diaziridine derivative, a class of compounds valued for their utility as photoaffinity labeling reagents and versatile intermediates in synthetic organic chemistry. Its significance lies in enabling precise molecular tagging and cross-linking studies, which are critical for probing biological interactions and developing advanced materials. This high-purity compound is essential for researchers and process chemists in pharmaceutical R&D, agrochemical synthesis, and advanced polymer science who require reliable, well-characterized building blocks.

Application

• Photoaffinity Labeling: Serves as a key reagent for covalent photo-crosslinking in proteomics and molecular biology to study protein-ligand interactions and binding sites.
• Pharmaceutical Intermediate: Used in the synthesis of complex drug candidates and bioactive molecules, particularly those requiring the introduction of a diaziridine moiety.
• Agrochemical Synthesis: Acts as a building block for developing novel pesticides and herbicides with specific modes of action.
• Polymer & Material Science: Employed as a cross-linking agent or functional monomer in the creation of specialty polymers and advanced materials.
• Chemical Biology Probes: Integral to the design and synthesis of probes for target identification and validation in drug discovery pipelines.
• Organic Synthesis Reagent: Functions as a versatile intermediate for constructing nitrogen-containing heterocycles and other complex organic architectures.

Basic Information

Product Name	1-(1,1-Dimethylethyl)-2-(1,1-Dimethyl-2-Phenylethyl)Diaziridin-3-One
CAS No.	19656-67-8
Molecular Formula	C16H24N2O
Molecular Weight	260.38 g/mol
Synonyms	tert-Butyl(1,1-dimethyl-2-phenylethyl)diaziridin-3-one; 3-tert-Butyl-1-(2-methyl-1-phenylpropyl)diaziridin-2-one; 1-(tert-Butyl)-2-(2-methyl-1-phenylpropyl)diaziridin-3-one; 1-(1,1-Dimethylethyl)-2-(1,1-dimethyl-2-phenylethyl)diaziridin-3-one; Diaziridin-3-one, 1-(1,1-dimethylethyl)-2-(1,1-dimethyl-2-phenylethyl)-; (1,1-Dimethylethyl)(1,1-dimethyl-2-phenylethyl)diaziridin-3-one
EINECS	Contact for details

Quality Control

Our 1-(1,1-Dimethylethyl)-2-(1,1-Dimethyl-2-Phenylethyl)Diaziridin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support research and cGMP applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.