Description

(4Ar,5S)-4A,5-Dimethyl-3-Propan-2-Ylidene-5,6,7,8-Tetrahydro-4H-Naphthalen-2-One CAS NO 19598-45-9 is a high-purity, stereochemically defined organic compound belonging to the class of substituted tetrahydro-naphthalenones. This compound serves as a critical chiral intermediate or building block in advanced organic synthesis, particularly for the development of complex molecules. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams working on novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to construct complex molecular architectures with defined three-dimensional configurations.
• Agrochemical Research: Potential intermediate in the synthesis of advanced, biologically active compounds for crop protection.
• Material Science: Serves as a precursor for the development of specialty polymers or organic electronic materials with specific optical or electronic properties.
• Academic & Contract Research: Used in university and CRO laboratories for methodological development in organic chemistry and catalysis studies.
• Flavor & Fragrance Industry: Potential starting material for the synthesis of complex terpenoid-like aroma molecules.

Basic Information

Item	Details
Product Name	(4Ar,5S)-4A,5-Dimethyl-3-Propan-2-Ylidene-5,6,7,8-Tetrahydro-4H-Naphthalen-2-One
CAS No.	19598-45-9
Molecular Formula	C₁₅H₂₀O
Molecular Weight	216.32 g/mol
Synonyms	(4aR,5S)-4a,5-Dimethyl-3-(propan-2-ylidene)-4a,5,6,7,8,8a-hexahydronaphthalen-2(4H)-one; (4aR,5S)-4a,5-Dimethyl-3-isopropylidene-4a,5,6,7,8,8a-hexahydro-2(4H)-naphthalenone; 2(4H)-Naphthalenone, 4a,5,6,7,8,8a-hexahydro-4a,5-dimethyl-3-(1-methylethylidene)-, (4aR,5S)-; (4aR,5S)-4a,5-Dimethyl-3-(propan-2-ylidene)-5,6,7,8-tetrahydro-4H-naphthalen-2-one; CAS 19598-45-9
EINECS	Contact for details

Quality Control

Our (4Ar,5S)-4A,5-Dimethyl-3-Propan-2-Ylidene-5,6,7,8-Tetrahydro-4H-Naphthalen-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.