Description

Methyl 3-Hydroxy-4,4,4-Trichlorobutyrate is a specialized halogenated ester compound that serves as a versatile chiral building block and intermediate in advanced organic synthesis. Its molecular structure, featuring both a reactive ester group and a hydroxyl group adjacent to a trichloromethyl moiety, makes it valuable for constructing complex molecules with defined stereochemistry. This intermediate is particularly sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), especially in routes requiring stereoselective synthesis.
• Agrochemical Synthesis: Used in the development and manufacturing of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Fine Chemical Production: Serves as a building block for various specialty chemicals, including flavors, fragrances, and performance materials.
• Organic Synthesis Research: Employed in academic and industrial R&D laboratories for method development and the construction of complex organic frameworks.
• Polymer Modifier: Can be utilized as a monomer or modifier in the synthesis of specialty polymers with unique properties.

Basic Information

Product Name	Methyl 3-Hydroxy-4,4,4-Trichlorobutyrate
CAS No.	19487-29-7
Molecular Formula	C5H7Cl3O3
Molecular Weight	221.46 g/mol
Synonyms	Methyl 3-Hydroxy-4,4,4-Trichlorobutanoate; 3-Hydroxy-4,4,4-Trichlorobutyric Acid Methyl Ester; 4,4,4-Trichloro-3-Hydroxybutyric Acid Methyl Ester; Methyl (R/S)-3-Hydroxy-4,4,4-Trichlorobutyrate; Butyric acid, 3-hydroxy-4,4,4-trichloro-, methyl ester; NSC 163045
EINECS	Contact for details

Quality Control

Our Methyl 3-Hydroxy-4,4,4-Trichlorobutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay (by HPLC or GC), chiral purity (if applicable), and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for intermediate manufacturing, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Chiral Purity (if specified)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.