Description

α-Hydroxy-γ-Butyrolactone is a versatile chiral building block and intermediate in organic synthesis. This compound is valued for its bifunctional structure, containing both a lactone ring and a hydroxyl group, which enables its use in the production of complex molecules. It is essential for manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various active pharmaceutical ingredients (APIs), including nootropic agents and GABAergic compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its reactivity to create specific stereocenters.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals requiring high-purity intermediates.
• Polymer Chemistry: Acts as a monomer or co-monomer for synthesizing biodegradable polymers and polyesters with tailored properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and methodologies.
• Cosmetic Ingredients: Potential use in the synthesis of certain moisturizing or skin-conditioning agents.

Basic Information

Product Name	α-Hydroxy-γ-Butyrolactone
CAS No.	19444-84-9
Molecular Formula	C₄H₆O₃
Molecular Weight	102.09 g/mol
Synonyms	α-Hydroxy-γ-butyrolactone; 2-Hydroxydihydro-2(3H)-furanone; 3-Hydroxybutyric acid lactone; 2-Hydroxy-γ-butyrolactone; (R/S)-2-Hydroxy-γ-butyrolactone; (±)-2-Hydroxy-γ-butyrolactone; 2-Hydroxybutyrolactone; Tetrahydro-2-hydroxy-2-furanone
EINECS	243-094-0

Quality Control

Our α-Hydroxy-γ-Butyrolactone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, chiral purity, and impurity profile determination, to ensure it meets the high standards required for synthesis. Certificates of Analysis (COA) documenting identity, purity, and specific tests are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.