Description

4,8-Dioxo-2-Adamantanecarboxylic Acid tert-Butyl Ester is a high-purity, functionalized adamantane derivative serving as a critical advanced intermediate in organic synthesis. Its unique bridged-ring structure and protected carboxylic acid group make it a valuable building block for constructing complex molecular architectures with enhanced thermal and chemical stability. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and advanced materials sectors for developing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and viral infections, leveraging the adamantane scaffold's bioactivity.
• Advanced Material Synthesis: Building block for high-performance polymers, resins, and dendrimers requiring rigid, thermally stable molecular components.
• Organic Light-Emitting Diode (OLED) Research: Used in the development of electron-transporting or host materials for more efficient and stable display technologies.
• Ligand and Catalyst Development: Serves as a backbone for creating sterically demanding, robust ligands used in asymmetric catalysis and organometallic chemistry.
• Protease Inhibitor Research: Intermediate in the design and synthesis of protease inhibitors, where the adamantane core can impart metabolic stability.
• Academic & Process Chemistry: A versatile reagent for methodological studies and scale-up process development in complex molecule construction.

Basic Information

Item	Detail
Product Name	4,8-Dioxo-2-Adamantanecarboxylic Acid tert-Butyl Ester
CAS No.	19305-81-8
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	tert-Butyl 4,8-dioxoadamantane-2-carboxylate; 2-Adamantanecarboxylic acid, 4,8-dioxo-, 1,1-dimethylethyl ester; 4,8-Dioxotricyclo[3.3.1.13,7]decane-2-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 4,8-dioxotricyclo[3.3.1.13,7]decane-2-carboxylate; 4,8-Dioxoadamantane-2-carboxylic Acid t-Butyl Ester; t-Butyl 4,8-dioxoadamantane-2-carboxylate; Adamantane-2-carboxylic acid, 4,8-dioxo-, tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4,8-Dioxo-2-Adamantanecarboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to moisture and should be handled under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.