Description

2-Amino-5-Ethyl-Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its functionalized thiophene scaffold, which serves as a critical precursor for developing novel pharmaceuticals and agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a monomer or building block for conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments due to the chromophoric properties of the thiophene ring.
• Chemical Research & Development: A valuable reagent for methodological studies in organic chemistry, including cyclization and cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Item	Detail
Product Name	2-Amino-5-Ethyl-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	19156-63-9
Molecular Formula	C8H11NO2S
Molecular Weight	185.24 g/mol
Synonyms	Methyl 2-Amino-5-ethylthiophene-3-carboxylate; 5-Ethyl-2-aminothiophene-3-carboxylic acid methyl ester; 2-Amino-5-ethyl-3-thiophenecarboxylic acid methyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-ethyl-, methyl ester; Methyl 5-ethyl-2-aminothiophene-3-carboxylate; 19156-63-9; 5-Ethyl-2-aminothiophene-3-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Ethyl-Thiophene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.