Description

(S)-4-Phenylbutane-2,3-Dienoic Acid is a chiral allenic carboxylic acid derivative, serving as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an allene moiety and a stereogenic center, makes it a versatile building block for constructing complex, optically active molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to create complex molecular architectures with defined chirality.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new drug candidates, particularly in fragment-based drug design.
• Agrochemical Development: Serves as an intermediate in the synthesis of chiral pesticides and herbicides.
• Ligand and Catalyst Synthesis: Useful for preparing chiral ligands and organocatalysts used in enantioselective transformations.
• Academic Research: A valuable tool for studying allene chemistry and developing new synthetic methodologies in university and institutional labs.

Basic Information

Product Name	(S)-4-Phenylbutane-2,3-Dienoic Acid
CAS No.	19131-89-6
Molecular Formula	C10H8O2
Molecular Weight	160.17 g/mol
Synonyms	(S)-4-Phenyl-2,3-butadienoic Acid; (S)-4-Phenylbuta-2,3-dienoic Acid; (S)-2,3-Butadienoic acid, 4-phenyl-; (S)-4-Phenylbutadienoic Acid; (S)-Allenylphenylacetic Acid
EINECS	Contact for details

Quality Control

Our (S)-4-Phenylbutane-2,3-Dienoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee reproducible performance in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.