Description

[1,3,2]Dioxaborinan-2-Ol is a versatile organoboron compound that serves as a crucial intermediate in modern synthetic chemistry. Its primary value lies in its ability to act as a protected boronic acid equivalent, offering enhanced stability and handling characteristics for complex coupling reactions. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for their synthesis pipelines.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly for pharmaceuticals and liquid crystals.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing aryl or heteroaryl groups.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and insecticides that require specific boron-containing scaffolds.
• Material Science & OLED Development: Acts as a precursor for creating organic light-emitting diode (OLED) materials and other functional polymers.
• Chemical Research & Development: A valuable tool for academic and industrial R&D chemists exploring new synthetic methodologies and boron chemistry.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	[1,3,2]Dioxaborinan-2-Ol
CAS No.	19118-85-5
Molecular Formula	C4H9BO3
Molecular Weight	115.92 g/mol
Synonyms	2-Hydroxy-1,3,2-dioxaborinane; 1,3,2-Dioxaborinan-2-ol; 2-Borono-1,3-propanediol cyclic ester; Cyclic propylene glycol boronic ester; 5-Hydroxy-1,3,2-dioxaborinane; Propylene glycol cyclic boronate; PG boronate; Boronic acid, B-(2-hydroxyethyl)-, cyclic ester with 1,3-propanediol
EINECS	Contact for details

Quality Control

Our [1,3,2]Dioxaborinan-2-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	95 - 100 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.