Description

3-(2-Chloro-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester is a high-purity organic ester building block of significant importance in advanced chemical synthesis. Its core value lies in its versatile β-ketoester functionality, which serves as a critical precursor for constructing complex heterocyclic and pharmaceutical intermediates. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality raw materials for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key starting material or synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing chlorinated aromatic and β-ketoester motifs.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where its chlorophenyl group contributes to biological activity.
• Fine Chemical Building Block: Employed in organic synthesis for constructing complex molecules via Claisen condensations, Michael additions, and cyclization reactions.
• Research & Development (R&D): Serves as a valuable reagent in academic and industrial laboratories for method development and exploring new chemical entities.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized dyes and organic pigments due to its aromatic ketone structure.
• Ligand and Catalyst Preparation: Can be utilized in the preparation of specialized ligands for metal-catalyzed reactions.

Basic Information

Product Name	3-(2-Chloro-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester
CAS No.	19112-35-7
Molecular Formula	C11H11ClO3
Molecular Weight	226.66 g/mol
Synonyms	Ethyl 3-(2-Chlorophenyl)-3-oxopropanoate; 2-Chlorobenzoylacetic Acid Ethyl Ester; Ethyl 2-Chlorobenzoylacetate; 3-Oxo-3-(2-chlorophenyl)propionic Acid Ethyl Ester; β-Keto Ester Derivative; Ethyl (2-Chlorobenzoyl)acetate; 1-(2-Chlorophenyl)-3-ethoxy-1,3-propanedione (enol form); CAS 19112-35-7
EINECS	Contact for details

Quality Control

Our 3-(2-Chloro-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.