Description

4-Bromo-4-Phenylbutyric Acid is a versatile brominated aromatic carboxylic acid that serves as a key chiral building block and intermediate in advanced organic synthesis. Its molecular structure, featuring both a reactive bromine atom and a carboxylic acid functional group, makes it invaluable for constructing complex molecules through various coupling and cyclization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and plant growth regulators, leveraging its phenylbutyric acid backbone.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials and liquid crystal monomers.
• Peptidomimetics & Bioactive Molecule Development: Employed in medicinal chemistry to create peptide analogs and other bioactive compounds with enhanced stability.
• Cross-Coupling Reactions: The bromine moiety makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, and Negishi couplings to form carbon-carbon bonds.
• Chiral Auxiliary & Resolving Agent Synthesis: Utilized in the preparation of chiral auxiliaries and agents for the separation of enantiomers.

Basic Information

Product Name	4-Bromo-4-Phenylbutyric Acid
CAS No.	19078-75-2
Molecular Formula	C10H11BrO2
Molecular Weight	243.10 g/mol
Synonyms	4-Bromo-4-phenylbutanoic acid; γ-Bromo-γ-phenylbutyric acid; 4-Phenyl-4-bromobutyric acid; (4-Bromo-4-phenyl)butyric acid; Butyric acid, 4-bromo-4-phenyl-; 19078-75-2; NSC 404058; 4-Brom-4-phenylbuttersäure (German)
EINECS	Contact for details

Quality Control

Every batch of our 4-Bromo-4-Phenylbutyric Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and GC, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and meet the stringent requirements of our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.