Description

2-((2-Chlorophenylamino)Methylene)Malonic Acid Diethyl Ester is a key synthetic intermediate characterized by its reactive malonate ester and anilino-methylene functional groups. This compound matters for its versatility in constructing complex heterocyclic and pharmaceutical scaffolds, enabling efficient synthesis pathways. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of quinoline, quinolone, and other nitrogen-containing heterocyclic compounds with potential biological activity.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, leveraging its reactive site for molecular diversification.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty chemicals requiring specific chlorophenyl-substituted structures.
• Academic & Industrial Research: Employed in method development and exploratory chemistry for creating novel chemical entities and libraries.
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	2-((2-Chlorophenylamino)Methylene)Malonic Acid Diethyl Ester
CAS No.	19056-78-1
Molecular Formula	C14H16ClNO4
Molecular Weight	297.74 g/mol
Synonyms	Diethyl 2-[(2-Chlorophenylamino)methylene]malonate; Diethyl (2-Chloroanilino)methylene malonate; 2-[(2-Chloroanilino)methylene]malonic Acid Diethyl Ester; Ethyl 2-((2-Chlorophenylamino)methylene)malonate; (2-Chloroanilino)methylene Malonic Acid Diethyl Ester; Propanedioic acid, [(2-chlorophenyl)amino]methylene-, diethyl ester; Diethyl (Z)-2-((2-chlorophenylamino)methylene)malonate
EINECS	Contact for details

Quality Control

Our 2-((2-Chlorophenylamino)Methylene)Malonic Acid Diethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics is provided with every shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.