Description

Ethyl 4-Hydroxy-3-Nitrobenzoate is a high-purity organic ester compound, serving as a versatile chemical intermediate in advanced synthesis. Its value lies in the strategic positioning of its functional groups—a phenolic hydroxyl, a nitro group, and an ester—which enable precise chemical modifications. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzoate core.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators where the nitro and hydroxy groups are pivotal for bioactivity.
• Dye and Pigment Precursor: Serves as a starting material for the manufacture of azo dyes and other complex colorants due to its aromatic nitro functionality.
• Liquid Crystal & OLED Material Research: Investigated as a synthetic intermediate for advanced electronic materials requiring specific polarity and molecular geometry.
• Polymer Modification Agent: Employed to introduce specific functional groups into polymer chains to alter material properties like adhesion or solubility.
• Organic Synthesis Reagent: A valuable reagent in academic and industrial laboratories for multi-step organic transformations, including esterifications and nitro-group reductions.

Basic Information

Product Name	Ethyl 4-Hydroxy-3-Nitrobenzoate
CAS No.	19013-10-6
Molecular Formula	C9H9NO5
Molecular Weight	211.17 g/mol
Synonyms	4-Hydroxy-3-nitrobenzoic Acid Ethyl Ester; Benzoic Acid, 4-Hydroxy-3-nitro-, Ethyl Ester; Ethyl 4-Hydroxy-3-nitrobenzoate; 3-Nitro-4-hydroxybenzoic Acid Ethyl Ester; Ethyl 3-Nitro-4-hydroxybenzoate; Ethyl 3-Nitroparaben; 19013-10-6; NSC 403697
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-3-Nitrobenzoate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for use in sensitive applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.