Description

1-(4-Bromo-Phenyl)-4,4,4-Trifluoro-Butane-1,3-Dione is a high-purity fluorinated diketone compound, serving as a versatile and critical building block in advanced chemical synthesis. Its unique structure, featuring both a bromophenyl group and a trifluoromethyl-substituted diketone moiety, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated or brominated aromatic systems for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group is a common pharmacophore for improving efficacy.
• Ligand and Catalyst Development: Serves as a starting material for β-diketone ligands used in coordination chemistry and catalysis, especially for metal complexes in asymmetric synthesis.
• Advanced Material Precursor: Employed in the development of organic electronic materials, such as OLEDs or semiconductors, where its structure can contribute to electron-transport properties.
• Chemical Research (R&D): A valuable scaffold in medicinal and combinatorial chemistry for library synthesis and structure-activity relationship (SAR) studies.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoromethyl-acetyl (CF3COCH2-) functionality into target molecules, a sought-after modification in modern drug design.

Basic Information

Product Name	1-(4-Bromo-Phenyl)-4,4,4-Trifluoro-Butane-1,3-Dione
CAS No.	18931-61-8
Molecular Formula	C10H6BrF3O2
Molecular Weight	295.06 g/mol
Synonyms	4'-Bromo-2,2,2-trifluoroacetophenone; 4-Bromophenyl trifluoroacetyl ketone; 1-(4-Bromophenyl)-4,4,4-trifluorobutane-1,3-dione; 4'-Bromo-α,α,α-trifluoroacetophenone; 4-Bromo-α,α,α-trifluoroacetophenone; p-Bromophenyl trifluoroacetyl methane; 4-Bromo-2,2,2-trifluoro-1-phenyl-1,3-butanedione; (4-Bromophenyl)trifluoroacetyl methane
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-Phenyl)-4,4,4-Trifluoro-Butane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.