Description

1-(4-Chlorophenyl)-4,4,4-trifluoro-1,3-butanedione is a versatile fluorinated diketone building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoromethylated β-diketone structure, which imparts valuable properties to target molecules, such as enhanced metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex intermediates, active ingredients, and novel materials.

Application

• As a key fluorinated synthon in pharmaceutical research for the development of new drug candidates.
• As a chelating ligand precursor in the synthesis of metal-organic complexes and catalysts.
• In agrochemical research for creating novel active ingredients with improved properties.
• As a versatile intermediate for synthesizing heterocyclic compounds, such as pyrazoles and isoxazoles.
• In materials science for the preparation of fluorinated polymers and advanced organic frameworks.
• For use in analytical chemistry as a derivatization agent or a standard for method development.

Basic Information

Product Name	1-(4-Chlorophenyl)-4,4,4-trifluoro-1,3-butanedione
CAS No.	18931-60-7
Molecular Formula	C10H6ClF3O2
Molecular Weight	250.60 g/mol
Synonyms	4'-Chloro-2,2,2-trifluoroacetophenone; 4-Chlorophenyl trifluoroacetyl ketone; 1-(4-Chlorophenyl)-1,3-butanedione, 4,4,4-trifluoro-; 4,4,4-Trifluoro-1-(4-chlorophenyl)-1,3-butanedione; p-Chlorophenyl trifluoroacetyl ketone; 4-Chlorobenzoyltrifluoroacetone; 1-(4-Chlorophenyl)-4,4,4-trifluorobutane-1,3-dione
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-4,4,4-trifluoro-1,3-butanedione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. Ensure the container is kept tightly sealed to prevent contamination and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.