Description

Z-Ala-Nva-Oh is a protected dipeptide building block, specifically an N-benzyloxycarbonyl (Z) protected alanine-valine derivative. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure and sequence. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for drug discovery and development projects.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled, sequential assembly of custom peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics, including enzyme inhibitors and receptor agonists/antagonists.
• Bioconjugation: Serves as a linker or spacer molecule in the creation of peptide-drug conjugates and other bioconjugates.
• Chemical Biology: Employed in the synthesis of peptide probes for studying protein-protein interactions and cellular processes.
• Material Science: A precursor for designing peptide-based polymers and biomimetic materials with specific functional properties.

Basic Information

Product Name	Z-Ala-Nva-Oh
CAS No.	18921-54-5
Molecular Formula	C16H22N2O5
Molecular Weight	322.36 g/mol
Synonyms	N-(Benzyloxycarbonyl)-L-alanyl-L-norvaline; Z-L-Ala-L-Nva-OH; N-Cbz-L-alanyl-L-norvaline; Benzyl N-[(2S)-1-[[(2S)-1-hydroxy-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]carbamate; Cbz-Ala-Nva-OH; Z-Ala-Nva; Nα-Cbz-L-alanyl-L-norvaline; L-Alanine, N-[(phenylmethoxy)carbonyl]-, (S)-, compd. with (S)-2-amino-1-pentanoic acid (1:1)
EINECS	Contact for details

Quality Control

Our Z-Ala-Nva-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.