Description

4-Iodo-3-Thiophenecarbaldehyde is a versatile and highly functionalized heterocyclic building block, primarily valued for its reactive aldehyde and halogen substituents on the thiophene ring. This compound is essential for facilitating complex molecular construction in advanced organic synthesis, particularly in cross-coupling and condensation reactions. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand & Catalyst Development: The iodine and aldehyde groups allow for functionalization into complex ligands for transition metal catalysis.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring novel heterocyclic chemistry, Suzuki-Miyaura, Stille, and Sonogashira cross-coupling reactions.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments with specific optical properties.

Basic Information

Product Name	4-Iodo-3-Thiophenecarbaldehyde
CAS No.	18799-84-3
Molecular Formula	C5H3IOS
Molecular Weight	253.05 g/mol
Synonyms	3-Formyl-4-iodothiophene; 4-Iodothiophene-3-carboxaldehyde; 4-Iodo-3-thiophenecarboxaldehyde; 4-Iodothiophene-3-carbaldehyde; 3-Thiophenecarboxaldehyde, 4-iodo-; Thiophene-3-carbaldehyde, 4-iodo-
EINECS	Contact for details

Quality Control

Our 4-Iodo-3-Thiophenecarbaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.