Description

4-Bromothiophene-2-Carboxaldehyde is a versatile brominated heterocyclic aldehyde that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde group and a bromine atom on a thiophene ring, makes it a highly reactive and valuable intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of new generation pesticides, herbicides, and fungicides due to its bioactive thiophene core.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and sensors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Research & Development: A fundamental reagent for Suzuki, Stille, and other cross-coupling reactions, as well as for further functionalization via the aldehyde group (e.g., reductive amination, condensation).
• Dye & Pigment Industry: Acts as an intermediate in the synthesis of specialized dyes and pigments with unique optical properties.

Basic Information

Product Name	4-Bromothiophene-2-Carboxaldehyde
CAS No.	18791-75-8
Molecular Formula	C5H3BrOS
Molecular Weight	191.05 g/mol
Synonyms	2-Bromo-5-formylthiophene; 5-Bromo-2-thiophenecarboxaldehyde; 4-Bromo-2-thiophenecarbaldehyde; 4-Bromothiophene-2-carbaldehyde; 2-Formyl-5-bromothiophene; 5-Bromothiophene-2-carboxaldehyde; 4-Bromo-2-formylthiophene
EINECS	Contact for details

Quality Control

Our 4-Bromothiophene-2-Carboxaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.