Description

(2S)-5,6-Dihydroxy-2,3-Dihydro-1H-Indole-2-Carboxylic Acid is a chiral, dihydroxy-substituted indoline derivative that serves as a critical synthetic intermediate and building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is integral to the development of complex molecules with specific stereochemistry and biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular systems.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive indoline core.
• Fine Chemical Synthesis: Serves as a versatile building block for creating specialty chemicals, dyes, and advanced materials.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and for probing biological pathways.
• Asymmetric Catalysis: Utilized as a ligand or a chiral auxiliary in catalytic reactions to induce stereoselectivity.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2S)-5,6-Dihydroxy-2,3-Dihydro-1H-Indole-2-Carboxylic Acid
CAS No.	18766-67-1
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	(2S)-2,3-Dihydro-5,6-dihydroxy-1H-indole-2-carboxylic acid; L-Adrenochrome Monocarboxylic Acid; (S)-5,6-Dihydroxyindoline-2-carboxylic Acid; 5,6-Dihydroxy-DL-indole-2-carboxylic Acid (racemic mixture); 2-Carboxy-5,6-dihydroxyindoline; 18766-67-1; NSC 163022
EINECS	Contact for details

Quality Control

Our (2S)-5,6-Dihydroxy-2,3-Dihydro-1H-Indole-2-Carboxylic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.