Description

5-Chloro-2-Phenyl-Benzofuran (CAS NO 18761-36-9) is a halogenated benzofuran derivative that serves as a versatile and high-value synthetic intermediate. Its core value proposition lies in its rigid, fused-ring structure, which provides a key scaffold for constructing more complex molecules in advanced research and development. This compound is particularly needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its halogenated aromatic system for bioactivity.
• Material Science Precursor: Serves as a monomer or precursor in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport materials.
• Ligand Synthesis: The benzofuran core can be functionalized to create specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Utilized in the design of fluorescent dyes and molecular probes for biochemical sensing and imaging applications.
• Academic & Contract Research: A critical reagent for methodological studies in organic synthesis and medicinal chemistry within university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	5-Chloro-2-Phenyl-Benzofuran
CAS No.	18761-36-9
Molecular Formula	C14H9ClO
Molecular Weight	228.67 g/mol
Synonyms	5-Chloro-2-phenylbenzofuran; 2-Phenyl-5-chlorobenzofuran; 5-Chloro-2-phenyl-1-benzofuran; Benzofuran, 5-chloro-2-phenyl-; 18761-36-9; 5-Chloro-2-phenyl-benzo[b]furan
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Phenyl-Benzofuran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.