Description

(1R,6α)-4,5α-Dihydroxy-3-Methyl-7-Oxabicyclo[4.1.0]Hept-3-En-2-One is a high-purity, specialized bicyclic lactone compound with a complex stereochemistry that is critical for advanced synthetic applications. This compound serves as a valuable chiral building block and key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially those with complex cyclic or bridged ring systems.
• Agrochemical Synthesis: Used in the creation of advanced, biologically active compounds for crop protection and pest management solutions.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Institutional Research: A valuable compound for methodological studies in organic synthesis, total synthesis projects, and investigating reaction mechanisms.
• Material Science Precursor: Potential use as a monomer or building block for synthesizing polymers with specific architectural features.

Basic Information

Product Name	(1R,6α)-4,5α-Dihydroxy-3-Methyl-7-Oxabicyclo[4.1.0]Hept-3-En-2-One
CAS No.	18746-82-2
Molecular Formula	C8H10O4
Molecular Weight	170.16 g/mol
Synonyms	4,5α-Dihydroxy-3-methyl-7-oxabicyclo[4.1.0]hept-3-en-2-one; (1R,6α)-4,5α-Dihydroxy-3-methyl-7-oxabicyclo[4.1.0]hept-3-en-2-one; 7-Oxabicyclo[4.1.0]hept-3-ene-2-one, 4,5-dihydroxy-3-methyl-, (1R,6α)-; Bicyclic lactone derivative; 3-Methyl-4,5α-dihydroxy-7-oxabicyclo[4.1.0]hept-3-en-2-one
EINECS	Contact for details

Quality Control

Our (1R,6α)-4,5α-Dihydroxy-3-Methyl-7-Oxabicyclo[4.1.0]Hept-3-En-2-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and research-grade material supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.