Description

7-Chloro-4-Hydroxy-2H-Chromen-2-One is a versatile halogenated coumarin derivative that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique molecular structure, featuring both chloro and hydroxy substituents on the coumarin core, makes it a valuable precursor for developing novel compounds with specific biological and photophysical properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to create new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the coumarin scaffold is active.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, leveraging its bioactivity as a core structure for crop protection agents.
• Fluorescent Probe & Dye Synthesis: Serves as a precursor for creating specialized fluorescent dyes and molecular probes used in biochemical assays and diagnostic imaging.
• Organic Light-Emitting Diode (OLED) Materials: A starting material for synthesizing electron-transport or emissive layer materials in OLED devices due to the tunable electronic properties of the coumarin system.
• Academic & Industrial R&D: Fundamental reagent in organic synthesis for constructing complex heterocyclic compounds and studying structure-activity relationships (SAR).
• Cosmetic Ingredient Synthesis: Potential intermediate for UV-absorbing agents or other functional ingredients in specialty cosmetic formulations.

Basic Information

Product Name	7-Chloro-4-Hydroxy-2H-Chromen-2-One
CAS No.	18735-81-4
Molecular Formula	C9H5ClO3
Molecular Weight	196.59 g/mol
Synonyms	7-Chloro-4-hydroxycoumarin; 4-Hydroxy-7-chlorocoumarin; 7-Chloro-4-hydroxy-2H-1-benzopyran-2-one; 7-Chloro-4-hydroxy-2H-chromen-2-one; 7-Chloro-4-hydroxy-2-chromenone; 7-Chloro-4-hydroxy-2-oxo-2H-chromene; 4-Hydroxy-7-chloro-2H-chromen-2-one; NSC 403169
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Hydroxy-2H-Chromen-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	258°C - 262°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.