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Diethyl 2-(2-Bromoethyl)-Malonate CAS NO 18721-64-7


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CAS No.:18721-64-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Diethyl 2-(2-Bromoethyl)-Malonate is a versatile brominated malonate ester, a key building block in organic synthesis. Its value lies in its dual functionality, featuring both a reactive bromoethyl group and a malonate moiety, making it an essential intermediate for constructing complex molecular frameworks. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for applications such as cyclopropanation, ring formation, and the synthesis of active pharmaceutical ingredients (APIs).

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug molecules, particularly those containing cyclopropane or other constrained ring systems.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific carbon chain extensions are required.
  • Fine Chemical Manufacturing: Serves as a building block for specialty chemicals, flavors, and fragrances.
  • Organic Synthesis Reagent: Employed in cyclopropanation reactions, Michael additions, and alkylation processes to introduce functionalized ethyl groups.
  • Material Science Research: Investigated as a monomer or cross-linking agent in the development of novel polymers and functional materials.
  • Academic & R&D: A valuable reagent for methodological development and exploring new synthetic pathways in university and industrial laboratories.

Basic Information

Product Name Diethyl 2-(2-Bromoethyl)-Malonate
CAS No. 18721-64-7
Molecular Formula C9H15BrO4
Molecular Weight 267.12 g/mol
Synonyms Diethyl (2-bromoethyl)malonate; 2-Bromoethylmalonic Acid Diethyl Ester; Malonic Acid, (2-Bromoethyl)-, Diethyl Ester; (2-Bromoethyl)propanedioic Acid Diethyl Ester; Diethyl 2-Bromoethylmalonate; Propanedioic Acid, (2-Bromoethyl)-, 1,3-Diethyl Ester; 18721-64-7; NSC 404088
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Quality Control

Our Diethyl 2-(2-Bromoethyl)-Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade specifications for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption and decomposition.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC/HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Related Substances (GC/HPLC) Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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