Description

6-Methyl-α-2-Pyridyl-2-Trifluoromethyl Quinoline-4-Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Chemical Research & Development: Serves as a versatile precursor for creating novel quinoline and pyridine-based derivatives in academic and industrial R&D labs.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and pesticides due to its bioactive heterocyclic core.
• Material Science Research: Investigated as a potential ligand or component in the creation of specialized organic electronic materials and catalysts.

Basic Information

Product Name	6-Methyl-α-2-Pyridyl-2-Trifluoromethyl Quinoline-4-Methanol
CAS No.	18709-90-5
Molecular Formula	C₁₈H₁₅F₃N₂O
Molecular Weight	332.32 g/mol
Synonyms	4-Quinolinemethanol, 6-methyl-α-2-pyridinyl-2-(trifluoromethyl)-; 6-Methyl-α-(2-pyridinyl)-2-(trifluoromethyl)-4-quinolinemethanol; 2-(Trifluoromethyl)-6-methyl-α-(2-pyridinyl)-4-quinolinemethanol; α-(2-Pyridyl)-2-trifluoromethyl-6-methyl-4-quinolinemethanol; 18709-90-5; Quinoline-4-methanol derivative
EINECS	Contact for details

Quality Control

Our 6-Methyl-α-2-Pyridyl-2-Trifluoromethyl Quinoline-4-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.