Description

2-(Hydroxymethyl)-5-Oxo-3-(3-Pyridyl)Pyrrolidine-2-Carboxylic Acid Ethyl Ester is a high-purity pyrrolidine derivative that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both a hydroxymethyl group and a pyridyl substituent, makes it a versatile precursor for the development of complex, biologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Chemical Research & Development: Used as a building block for constructing complex heterocyclic frameworks and exploring new reaction pathways in medicinal chemistry.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced, targeted pesticides and herbicides due to its bioactive scaffold.
• Academic Research: Employed in university and institutional labs for studying asymmetric synthesis, catalysis, and the structure-activity relationships (SAR) of pyrrolidine-based compounds.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-(Hydroxymethyl)-5-Oxo-3-(3-Pyridyl)Pyrrolidine-2-Carboxylic Acid Ethyl Ester
CAS No.	18707-23-8
Molecular Formula	C13H16N2O4
Molecular Weight	264.28 g/mol
Synonyms	Ethyl 2-(Hydroxymethyl)-5-oxo-3-(3-pyridinyl)-1-pyrrolidinecarboxylate; 3-Pyridyl Proline Derivative; 2-(Hydroxymethyl)-5-oxo-3-(pyridin-3-yl)pyrrolidine-2-carboxylic acid ethyl ester; 18707-23-8; 5-Oxo-3-(3-pyridyl)-2-pyrrolidinecarboxylic acid ethyl ester, 2-(hydroxymethyl)-; Pyrrolidine-2-carboxylic acid, 2-(hydroxymethyl)-5-oxo-3-(3-pyridinyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 2-(Hydroxymethyl)-5-Oxo-3-(3-Pyridyl)Pyrrolidine-2-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured under controlled conditions and undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles to meet the exacting standards of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.