Description

α-2-Pyridyl-4-[2-Trifluoromethylquinoline]Methanol is a specialized heterocyclic organic compound featuring a quinoline core substituted with a trifluoromethyl group and a pyridylmethanol moiety. This unique molecular architecture makes it a high-value intermediate for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis sectors for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, or anti-cancer agents.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl and quinoline groups can enhance bioactivity and environmental stability.
• Material Science: Serves as a precursor for creating specialty polymers, liquid crystals, or organic light-emitting diodes (OLEDs) due to its rigid, conjugated structure.
• Chemical Synthesis: Employed in organic chemistry research as a versatile scaffold for constructing complex heterocyclic libraries via cross-coupling and functional group transformations.
• Ligand & Catalyst Development: The pyridyl and hydroxyl groups make it a potential candidate for designing novel ligands in coordination chemistry and catalysis.

Basic Information

Item	Details
Product Name	α-2-Pyridyl-4-[2-Trifluoromethylquinoline]Methanol
CAS No.	18706-55-3
Molecular Formula	C₁₆H₁₁F₃N₂O
Molecular Weight	304.27 g/mol
Synonyms	2-Pyridyl(2-trifluoromethyl-4-quinolyl)methanol; (2-Trifluoromethylquinolin-4-yl)(pyridin-2-yl)methanol; 4-(Hydroxy(pyridin-2-yl)methyl)-2-(trifluoromethyl)quinoline; α-(2-Pyridyl)-2-trifluoromethyl-4-quinolinemethanol; 2-Trifluoromethyl-4-(2-pyridylhydroxymethyl)quinoline; Quinoline, 2-(trifluoromethyl)-4-[(2-pyridinyl)hydroxymethyl]-; CAS 18706-55-3
EINECS	Contact for details

Quality Control

Our production of α-2-Pyridyl-4-[2-Trifluoromethylquinoline]Methanol adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. A Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment. We support cGMP and ISO compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and hygroscopic; therefore, handling under an inert atmosphere is recommended for long-term storage or when working with large quantities. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.