Description

6-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block distinguished by its unique trifluoromethyl and chloro substituents. This compound matters for its critical role in the synthesis of advanced pharmaceutical intermediates and agrochemicals, where it imparts desirable metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to develop advanced herbicides and fungicides, leveraging the trifluoromethyl group for enhanced efficacy and environmental profile.
• Material Science Research: Serves as a building block for creating organic electronic materials and fluorescent dyes due to its quinoline core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	6-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline
CAS No.	18706-21-3
Molecular Formula	C10H5ClF3NO
Molecular Weight	247.60 g/mol
Synonyms	4-Hydroxy-6-chloro-2-(trifluoromethyl)quinoline; 6-Chloro-4-hydroxy-2-trifluoromethylquinoline; 2-(Trifluoromethyl)-6-chloro-4-quinolinol; 4-Quinolinol, 6-chloro-2-(trifluoromethyl)-; Quinoline, 6-chloro-4-hydroxy-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.