Description

4'-Bromo-3'-Nitroacetophenone is a versatile and high-purity brominated aromatic ketone building block, essential for advanced organic synthesis. Its unique molecular structure, featuring both bromo and nitro substituents on the acetophenone core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its reactive halogen and nitro groups.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive polymers.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex azo dyes and other colored compounds.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4'-Bromo-3'-Nitroacetophenone
CAS No.	18640-58-9
Molecular Formula	C8H6BrNO3
Molecular Weight	244.04 g/mol
Synonyms	1-(4-Bromo-3-nitrophenyl)ethan-1-one; 3'-Nitro-4'-bromoacetophenone; 4-Bromo-3-nitroacetophenone; 1-Acetyl-4-bromo-3-nitrobenzene; p-Bromo-m-nitroacetophenone; 4-Bromo-3-nitroacetylbenzene; NSC 406122; Ethanone, 1-(4-bromo-3-nitrophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 4'-Bromo-3'-Nitroacetophenone is manufactured under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92°C - 96°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.