Description

Methyl 2-Acetylamino-3-Chloropropionate is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a protected amino group and an ester moiety, which makes it a versatile precursor for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of β-amino acid derivatives, peptidomimetics, and other bioactive compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific stereochemistry.
• Custom Synthesis & Contract Manufacturing: Serves as a critical starting material for custom synthesis projects and process development in fine chemical production.
• Academic & Industrial Research: Employed in medicinal chemistry and process chemistry R&D for exploring new synthetic routes and molecular entities.
• Peptide Chemistry: Acts as a protected amino acid ester derivative for the preparation of modified peptides and unnatural amino acids.

Basic Information

Product Name	Methyl 2-Acetylamino-3-Chloropropionate
CAS No.	18635-38-6
Molecular Formula	C6H10ClNO3
Molecular Weight	179.60 g/mol
Synonyms	Methyl N-Acetyl-3-chloroalaninate; Methyl (R,S)-2-Acetamido-3-chloropropionate; 2-Acetylamino-3-chloropropionic Acid Methyl Ester; 3-Chloro-N-acetylalanine Methyl Ester; N-Acetyl-3-chloroalanine Methyl Ester; Methyl 2-Acetamido-3-chloropropionate; Alanine, 3-chloro-N-acetyl-, methyl ester; Methyl α-acetamido-β-chloropropionate
EINECS	Contact for details

Quality Control

Our Methyl 2-Acetylamino-3-Chloropropionate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Specify enantiomer (Contact for details)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.