Description

(2-Methylphenyl)Phenylphosphinic Acid is a specialized organophosphorus compound featuring a phosphinic acid functional group linked to phenyl and o-tolyl substituents. This unique structure makes it a valuable intermediate and ligand precursor in advanced chemical synthesis and materials science. It is primarily utilized by pharmaceutical, agrochemical, and specialty polymer industries for research, development, and high-purity manufacturing processes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring chiral phosphine ligands or phosphorus-containing scaffolds.
• Catalyst & Ligand Synthesis: Used as a precursor for manufacturing chiral phosphine ligands, which are critical in asymmetric catalysis for producing enantiomerically pure compounds.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators that incorporate phosphinic acid moieties for enhanced activity.
• Flame Retardant Synergist: Acts as a reactive intermediate or additive in the production of flame-retardant polymers and materials.
• Coordination Chemistry: Functions as a chelating agent or ligand for metal ions, useful in creating metal-organic frameworks (MOFs) or extraction agents.
• Polymer Modification: Incorporated into polymer chains to impart specific properties such as improved thermal stability, adhesion, or flame resistance.
• Organic Synthesis Reagent: Utilized in various organic transformations, including phosphorylation reactions and as a source of the phosphinic acid group.

Basic Information

Product Name	(2-Methylphenyl)Phenylphosphinic Acid
CAS No.	18593-18-5
Molecular Formula	C13H13O2P
Molecular Weight	232.21 g/mol
Synonyms	o-Tolyl(phenyl)phosphinic Acid; (2-Methylphenyl)(phenyl)phosphinic Acid; Phenyl-o-tolylphosphinic Acid; 2-Methylbenzenephenylphosphinic Acid; Benzenephenylphosphinic Acid, 2-methyl-; Phosphinic acid, P-phenyl-P-(2-methylphenyl)-; P-Phenyl-P-(o-tolyl)phosphinic Acid
EINECS	Contact for details

Quality Control

Our (2-Methylphenyl)Phenylphosphinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Specifications can be tailored to meet specific research-grade or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.