Description

Hydroxy-p-Tolyl-Acetic Acid is a versatile aromatic carboxylic acid derivative, serving as a key chiral building block and intermediate in advanced organic synthesis. Its molecular structure, featuring both a phenolic hydroxyl and an acetic acid group on a toluene backbone, makes it invaluable for constructing complex molecules with high stereochemical control. This compound is essential for research and production in the pharmaceutical and fine chemical sectors, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), chiral active pharmaceutical ingredients (APIs), and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific aromatic acid motifs.
• Fine Chemical & Specialty Chemistry: Employed as a building block for liquid crystals, dyes, pigments, and performance chemicals where structural integrity is paramount.
• Chiral Resolver & Ligand Precursor: Its structure is useful for developing chiral auxiliaries, catalysts, and ligands used in asymmetric synthesis.
• Research & Development: A valuable compound in academic and industrial R&D for exploring new synthetic pathways and novel chemical entities.

Basic Information

Product Name	Hydroxy-p-Tolyl-Acetic Acid
CAS No.	18584-20-8
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	(4-Hydroxyphenyl)acetic acid, methylphenol; 2-(4-Hydroxyphenyl)acetic acid; p-Hydroxyphenylacetic acid; 4-Hydroxyphenylacetic acid; 4-HPA; HPA; PHAA; (p-Hydroxyphenyl)acetic acid
EINECS	242-418-1

Quality Control

Our Hydroxy-p-Tolyl-Acetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and loss on drying, to ensure it meets exacting standards for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Melting Point	148°C - 152°C
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.