Description

2-Hydroxy-4-Methyl-Benzonitrile is a versatile aromatic nitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a phenolic hydroxyl and a nitrile group, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzofuran or benzoxazole cores.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized dyes, pigments, and optical brighteners.
• Ligand and Catalyst Development: Useful in creating chelating ligands for metal catalysts used in cross-coupling and other organic transformations.
• Polymer Chemistry: Monomer or modifier for engineering plastics and high-performance polymers.
• Organic Synthesis Research: Versatile starting material for academic and industrial R&D exploring new heterocyclic compounds.

Basic Information

Product Name	2-Hydroxy-4-Methyl-Benzonitrile
CAS No.	18495-14-2
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	4-Methyl-2-hydroxybenzonitrile; 2-Cyano-5-methylphenol; 5-Methylsalicylonitrile; 2-Hydroxy-p-tolunitrile; 4-Methylsalicylonitrile; o-Hydroxy-p-tolunitrile; 2-Hydroxy-4-methylbenzenecarbonitrile
EINECS	242-363-9

Quality Control

Our 2-Hydroxy-4-Methyl-Benzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.