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n-Tetradecyl-β-D-Maltoside CAS NO 18449-82-6


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CAS No.:18449-82-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Tetradecyl-β-D-Maltoside is a high-purity, non-ionic surfactant belonging to the alkyl glycoside family, specifically a maltoside derivative with a 14-carbon alkyl chain. This compound is valued for its effective membrane-solubilizing properties while maintaining protein stability, making it a critical reagent in structural biology and biochemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the purification and crystallization of membrane proteins.

Application

  • Membrane Protein Solubilization & Purification: A key detergent for extracting and stabilizing integral membrane proteins for downstream analysis.
  • Biophysical Studies: Used in techniques such as X-ray crystallography, cryo-electron microscopy, and NMR spectroscopy to study protein structure and function.
  • Liposome & Vesicle Preparation: Employed in the formation and manipulation of model membrane systems for drug delivery and membrane interaction studies.
  • Cell Lysis: An effective component in lysis buffers for gentle disruption of cell membranes while preserving protein activity.
  • Chromatography: Used in various chromatographic techniques, including affinity and size-exclusion chromatography, to purify sensitive biomolecules.
  • Diagnostic Assay Development: Serves as a stabilizing agent in immunoassays and other diagnostic kits that involve membrane-bound targets.

Basic Information

Product Name n-Tetradecyl-β-D-Maltoside
CAS No. 18449-82-6
Molecular Formula C₂₆H₅₀O₁₁
Molecular Weight 538.67 g/mol
Synonyms n-Tetradecyl-β-D-maltopyranoside; Tetradecyl β-D-maltoside; Dodecyl Maltoside (C14); C14 Maltoside; n-Tetradecyl-β-maltoside; β-n-Tetradecylmaltoside; Tetradecyl maltopyranoside; Anagrade® n-Tetradecyl-β-D-Maltoside
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Quality Control

Our n-Tetradecyl-β-D-Maltoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and critical micelle concentration (CMC). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). For long-term stability, consider storage under an inert atmosphere or in a desiccator.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Critical Micelle Concentration (CMC) 0.008 - 0.012 mM (in water at 25°C)
Water Content (KF) ≤ 2.0 %
Residue on Ignition ≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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