Description

7-Bromochroman-4-One is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core chromanone scaffold, functionalized with a bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and cardiovascular diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic electronic materials and advanced polymers due to its rigid, aromatic-fused structure.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce the chromanone moiety into more complex molecules.
• Flavor & Fragrance Industry: Utilized as an intermediate for synthesizing certain aroma chemicals with spicy or woody notes.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	7-Bromochroman-4-One
CAS No.	18442-22-3
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	7-Bromo-4-chromanone; 7-Bromo-2,3-dihydro-4H-1-benzopyran-4-one; 4-Chromanone, 7-bromo-; 7-Bromochromanone; 7-Bromo-4-chromone (common misnomer); 7-Bromo-3,4-dihydro-2H-1-benzopyran-4-one
EINECS	Contact for details

Quality Control

Our 7-Bromochroman-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.