Description

1,2:4,5-Di-o-Isopropylidene-β-D-Psicopyranose is a high-purity, protected sugar derivative widely used as a critical chiral building block in organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules with precise stereochemistry, essential for pharmaceutical and fine chemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of nucleoside analogs, carbohydrate-based drugs, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of nucleoside analogs and antiviral/anticancer agents.
• Carbohydrate Chemistry Research: Essential building block for constructing complex oligosaccharides and glycoconjugates.
• Fine Chemical Synthesis: Used in the preparation of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Agrochemical Development: Intermediate for creating chiral active ingredients in herbicides and pesticides.
• Academic & Industrial R&D: A valuable tool for methodological development in asymmetric synthesis and medicinal chemistry.
• Diagnostic Reagent Synthesis: Used in the production of labeled sugars and probes for biochemical assays.

Basic Information

Product Name	1,2:4,5-Di-o-Isopropylidene-β-D-Psicopyranose
CAS No.	18422-54-3
Molecular Formula	C12H20O6
Molecular Weight	260.28 g/mol
Synonyms	1,2:4,5-Di-O-isopropylidene-β-D-psicopyranose; Diacetone D-psicose; 1,2:4,5-Di-O-(1-methylethylidene)-β-D-psicopyranose; D-Psicose Diacetonide; 1,2:4,5-Di-O-isopropylidene-D-psicose; 1,2:4,5-Di-O-isopropylidene-psicofuranose; 18422-54-3; Di-O-isopropylidene-D-psicopyranose
EINECS	Contact for details

Quality Control

Our 1,2:4,5-Di-o-Isopropylidene-β-D-Psicopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-30° to -35° (c=1 in CHCl₃)
Melting Point	105°C - 110°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.