Description

(1R,4S)-1,7,7-Trimethylbicyclo[2.2.1]hept-2-ene is a high-purity, chiral bicyclic monoterpene derivative, valued for its specific stereochemistry and unique structural framework. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with precise stereocontrol. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-quality, stereochemically defined intermediates for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of terpene-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Fine Chemical & Fragrance Ingredient: Serves as a precursor for high-value aroma chemicals, flavors, and fragrances due to its camphor-related structure.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions and other cycloadditions to construct complex polycyclic frameworks in academic and industrial R&D.
• Catalyst & Ligand Development: Utilized as a backbone for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or modifying agent for specialty polymers with unique thermal or optical properties.

Basic Information

Product Name	(1R,4S)-1,7,7-Trimethylbicyclo[2.2.1]hept-2-ene
CAS No.	18383-34-1
Molecular Formula	C10H16
Molecular Weight	136.23 g/mol
Synonyms	(1R,4S)-(-)-Camphene; (-)-Camphene; L-Camphene; (1R,4S)-2,2-Dimethyl-3-methylenebicyclo[2.2.1]heptane; (1R,4S)-1,7,7-Trimethylbicyclo[2.2.1]hept-2-ene; (1R)-1,7,7-Trimethylbicyclo[2.2.1]hept-2-ene; (-)-2,2-Dimethyl-3-methylenenorbornane
EINECS	Contact for details

Quality Control

Our (1R,4S)-1,7,7-Trimethylbicyclo[2.2.1]hept-2-ene is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place at recommended room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Chiral Purity (GC/HPLC)	≥ 98.0% ee
Specific Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.