Description

Diethyl 3-Hydroxyglutarate is a versatile diester of 3-hydroxyglutaric acid, serving as a high-value chemical intermediate. Its bifunctional structure, featuring both ester and hydroxyl groups, makes it a critical building block for the synthesis of complex molecules. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct key pharmacophores and chiral centers.

Application

• Pharmaceutical Intermediate: Key starting material or chiral synthon for the synthesis of statin drugs, bioactive molecules, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators with specific stereochemistry.
• Polymer & Resin Modifier: Used in the production of specialty polyesters and coatings to introduce hydroxyl functionality, improving adhesion and cross-linking properties.
• Flavor & Fragrance Industry: Intermediate for the synthesis of lactones and other compounds that contribute to complex flavor and aroma profiles.
• Organic Synthesis Reagent: A valuable reagent in academic and industrial R&D for Michael additions, esterifications, and asymmetric synthesis.
• Cosmetic Ingredients: Potential precursor for emollients and skin-conditioning agents in high-end cosmetic formulations.

Basic Information

Item	Detail
Product Name	Diethyl 3-Hydroxyglutarate
CAS No.	18373-31-4
Molecular Formula	C9H16O5
Molecular Weight	204.22 g/mol
Synonyms	3-Hydroxyglutaric Acid Diethyl Ester; Diethyl 3-Hydroxypentanedioate; Ethyl 3-Hydroxyglutarate; 3-Hydroxy-1,5-pentanedioic Acid Diethyl Ester; DEHG; Diethyl 3-Hydroxy-1,5-pentanedioate
EINECS	Contact for details

Quality Control

Our Diethyl 3-Hydroxyglutarate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation [α] (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.