Description

Leucomycin A6 CAS NO 18361-48-3 is a macrolide antibiotic belonging to the leucomycin (kitasamycin) complex, valued for its potent antibacterial activity against Gram-positive and some Gram-negative bacteria. This compound is a critical intermediate and reference standard in pharmaceutical research and development, particularly for the synthesis and quality control of related antibiotic agents. It is essential for manufacturers and R&D laboratories in the pharmaceutical, veterinary medicine, and agrochemical sectors requiring high-purity bioactive components.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced macrolide antibiotics and derivatives.
• Reference Standard: Used in analytical laboratories for quality control, method validation, and identification via HPLC, LC-MS, or NMR.
• Microbiological Research: Employed in studies of antibacterial mechanisms, resistance profiling, and the development of new antimicrobial agents.
• Veterinary Medicine: A component in R&D for animal health products targeting bacterial infections.
• Agrochemical Research: Investigated for potential applications in plant protection and bactericidal formulations.
• Biochemical Studies: Utilized as a tool compound to study protein synthesis inhibition and ribosomal function.

Basic Information

Product Name	Leucomycin A6
CAS No.	18361-48-3
Molecular Formula	C41H67NO15
Molecular Weight	813.97 g/mol
Synonyms	Kitasamycin A6; Leucomycin V; Ayermycin; Kitasamycin; 9,3''-Di-O-acetylleucomycin A5; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-7-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our Leucomycin A6 is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure identity, purity, and potency, meeting the stringent requirements for pharmaceutical intermediates and reference standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results for assay, related substances, residual solvents, and microbiological parameters as applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.