Description

Leucomycin A4 CAS NO 18361-46-1 is a macrolide antibiotic belonging to the leucomycin (kitasamycin) complex, valued for its potent antibacterial activity against Gram-positive bacteria and certain mycoplasmas. Its significance lies in its role as a key intermediate and reference standard in pharmaceutical research, development, and quality control. This product is essential for manufacturers and R&D laboratories in the pharmaceutical, veterinary medicine, and agrochemical sectors requiring high-purity antibiotic compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced antibiotic formulations.
• Veterinary Medicine: Used in the development of treatments for bacterial infections in livestock and companion animals.
• Microbiological Research: Employed as a reference standard in studies of bacterial resistance mechanisms and antibiotic efficacy.
• Quality Control & Analytical Testing: Functions as a certified reference material (CRM) for HPLC, LC-MS, and other analytical methods to ensure batch consistency.
• Agrochemical Research: Investigated for potential applications in plant disease management due to its antibacterial properties.

Basic Information

Product Name	Leucomycin A4
CAS No.	18361-46-1
Molecular Formula	C₄₀H₆₇NO₁₄
Molecular Weight	785.96 g/mol
Synonyms	Kitasamycin A4; Leucomycin V; Ayermycin; Kitasamycin; Stereomycin; Antibiotic T 2636 C; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-7-[(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)oxy]-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
EINECS	242-225-8

Quality Control

Our Leucomycin A4 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets high-grade standards suitable for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.