Description

(3-Oxo-1,3-Dihydro-Isobenzofuran-1-Yl)-Acetonitrile is a versatile and high-purity organic intermediate characterized by its fused isobenzofuranone-acetonitrile structure. This compound is valued for its role as a key building block in the synthesis of complex molecules, offering a reactive nitrile group adjacent to a cyclic lactone moiety. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its unique heterocyclic scaffold.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and liquid crystals with specific optical or mechanical properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocycles and natural product analogs via reactions at the nitrile or lactone carbonyl group.
• Dye and Pigment Intermediate: Utilized in the synthesis of advanced organic colorants and photochromic materials due to its conjugated system potential.

Basic Information

Product Name	(3-Oxo-1,3-Dihydro-Isobenzofuran-1-Yl)-Acetonitrile
CAS No.	18327-98-5
Molecular Formula	C10H7NO2
Molecular Weight	173.17 g/mol
Synonyms	1-(Cyanomethyl)isobenzofuran-3(1H)-one; 1-(Cyanomethyl)-1,3-dihydro-2-benzofuran-3-one; 1,3-Dihydro-3-oxo-1-isobenzofuranacetonitrile; 3-Oxo-1,3-dihydro-1-isobenzofuranacetonitrile; Phthalidylacetonitrile; (3-Oxo-1,3-dihydroisobenzofuran-1-yl)acetonitrile; α-(3-Oxo-1,3-dihydro-2-benzofuranyl)acetonitrile
EINECS	Contact for details

Quality Control

Our (3-Oxo-1,3-Dihydro-Isobenzofuran-1-Yl)-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and research-standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.