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(2S)-1,2,3,4,4A,9,10,10Aα-Octahydro-1,1,4Aβ-Trimethyl-7-(1-Methylethyl)-2β,6-Phenanthrenediol 6-Acetate CAS NO 18326-14-2


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CAS No.:18326-14-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2S)-1,2,3,4,4A,9,10,10Aα-Octahydro-1,1,4Aβ-Trimethyl-7-(1-Methylethyl)-2β,6-Phenanthrenediol 6-Acetate CAS NO 18326-14-2 is a high-purity, stereochemically defined diterpenoid derivative. This compound is valued for its role as a key synthetic intermediate and reference standard in advanced pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of complex bioactive molecules.

Application

  • Pharmaceutical Intermediate: A critical building block for the synthesis of novel diterpenoid-based drug candidates and active pharmaceutical ingredients (APIs).
  • Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related compounds via HPLC, GC, or LC-MS.
  • Chemical Research: Serves as a starting material or model compound in organic synthesis and medicinal chemistry for exploring structure-activity relationships (SAR).
  • Natural Product Synthesis: A valuable intermediate in the total or semi-synthesis of complex natural products with diterpenoid skeletons.
  • Process Development: Utilized in scaling up synthetic routes and optimizing manufacturing processes for high-value fine chemicals.

Basic Information

Item Details
Product Name (2S)-1,2,3,4,4A,9,10,10Aα-Octahydro-1,1,4Aβ-Trimethyl-7-(1-Methylethyl)-2β,6-Phenanthrenediol 6-Acetate
CAS No. 18326-14-2
Molecular Formula C23H36O3
Molecular Weight 360.54 g/mol
Synonyms Abietic acid derivative; 6-Acetoxy-7-isopropyl-1,1,4a-trimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2-ol; (2S,4aR,10aS)-6-(Acetyloxy)-2-hydroxy-7-isopropyl-1,1,4a-trimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene; Diterpene alcohol acetate; 6β-Acetoxy-7-isopropyl-1,1,4aα-trimethyl-decahydrophenanthren-2β-ol
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is analyzed using advanced techniques like HPLC and GC to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system suitable for supplying materials for research and development under cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 97.0%
Related Substances (HPLC) Total impurities ≤ 3.0%
Any single unknown impurity ≤ 1.0%
Residual Solvents (GC) Complies with ICH Q3C guidelines
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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