Description

4-Cyclohexylbenzenethiol is a specialized organosulfur compound featuring a thiol (-SH) functional group attached to a biphenyl-like structure with a cyclohexyl substituent. This unique molecular architecture makes it a valuable intermediate for synthesizing complex molecules where the thiol group can act as a ligand or a reactive handle for further chemical modification. It is particularly sought after by research and development teams in the pharmaceutical and advanced materials sectors. The compound is supplied under stringent quality control to ensure consistency for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring thioether linkages or metal-binding motifs.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis, particularly in transition metal complexes for cross-coupling and other organic transformations.
• Polymer Modification: Acts as a chain-transfer agent or functional monomer to introduce thiol groups into polymers, altering their physical properties or enabling post-polymerization modifications.
• Material Science Research: Employed in the development of self-assembled monolayers (SAMs) on gold and other surfaces for sensor and electronic applications.
• Agrochemical Synthesis: Utilized as a precursor in creating novel compounds with potential biological activity for crop protection.
• Chemical Research: A versatile reagent in organic synthesis for constructing complex sulfur-containing heterocycles and other molecular architectures.

Basic Information

Product Name	4-Cyclohexylbenzenethiol
CAS No.	18325-50-3
Molecular Formula	C12H16S
Molecular Weight	192.32 g/mol
Synonyms	p-Cyclohexylbenzenethiol; (4-Cyclohexylphenyl)thiol; 4-Cyclohexylthiophenol; 1-Cyclohexyl-4-mercaptobenzene; 4-Cyclohexylbenzenethiol; 4-Cyclohexylphenyl mercaptan; NSC 163081
EINECS	Contact for details

Quality Control

Our 4-Cyclohexylbenzenethiol is manufactured under a quality management system to ensure batch-to-batch consistency and reliability. Each lot undergoes rigorous analytical testing, including chromatographic purity assessment and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support compliance with relevant regulatory frameworks for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. Due to the thiol functionality, prolonged exposure to air should be minimized to prevent oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.