Description

Uracil, Dimer, Syn- (8Ci) is a specific stereoisomer of a uracil dimer, a compound formed by the covalent linkage of two uracil bases. This high-purity chemical is a critical building block and reference standard in advanced organic synthesis and biochemical research. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleic acid chemistry, photobiology, and the development of novel therapeutic agents.

Application

• Nucleic Acid Research: As a model compound for studying UV-induced DNA/RNA damage and repair mechanisms.
• Photochemistry Studies: Investigating the photodynamic properties and stability of pyrimidine bases.
• Organic Synthesis: Serving as a key intermediate or precursor in the synthesis of modified nucleosides, nucleotides, and oligonucleotide analogs.
• Analytical Reference Standard: Used for method development, calibration, and quantification in HPLC, LC-MS, and other analytical techniques within quality control and research laboratories.
• Biochemical Probe Development: For creating tools to study enzyme interactions with damaged DNA substrates.

Basic Information

Product Name	Uracil, Dimer, Syn- (8Ci)
CAS No.	18324-22-6
Molecular Formula	C8H8N4O4
Molecular Weight	224.17 g/mol
Synonyms	syn-Cyclobutadipyrimidine; syn-Uracil Dimer; 1,3-Diazinane-2,4-dione, dimer, syn-; syn-Cyclobutane dipyrimidine; 5,5',6,6'-Tetrahydro-6,6'-dihydroxy-5,5'-bipyrimidine-2,2',4,4'(1H,1'H,3H,3'H)-tetrone (syn); Uracil photodimer (syn); syn-1,3-Dimethyluracil dimer
EINECS	Contact for details

Quality Control

Our Uracil, Dimer, Syn- (8Ci) is produced under stringent conditions to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and relevant physical data is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.