Description

4(3H)-Pyrimidinone, 6-Fluoro-2-Methyl- (8Ci) is a fluorinated pyrimidinone derivative, a high-value heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables targeted molecular design. Pharmaceutical and agrochemical research organizations need this material for creating new drug candidates and crop protection agents with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential precursor for the development of specialty chemicals and advanced organic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	4(3H)-Pyrimidinone, 6-Fluoro-2-Methyl- (8Ci)
CAS No.	18260-82-7
Molecular Formula	C5H5FN2O
Molecular Weight	128.10 g/mol
Synonyms	6-Fluoro-2-methylpyrimidin-4(3H)-one; 6-Fluoro-2-methyl-4(3H)-pyrimidinone; 2-Methyl-6-fluoropyrimidin-4(3H)-one; 6-Fluoro-2-methyl-3H-pyrimidin-4-one; 4-Hydroxy-6-fluoro-2-methylpyrimidine; 6-Fluoro-2-methyl-4-pyrimidinol; 6-Fluoro-2-methyl-4-hydroxypyrimidine; 18260-82-7
EINECS	Contact for details

Quality Control

Our 4(3H)-Pyrimidinone, 6-Fluoro-2-Methyl- (8Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.